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Table 2 Effect of phenylephrine on hemodynamic values in the preload dependent and independent groups

From: Prediction of preload dependency using phenylephrine-induced peripheral perfusion index during general anaesthesia: a prospective observational study

  

Preload dependent (n = 23)

Preload independent (n = 19)

Post-induction hypotension

1 min

2 min

P value

Post-induction hypotension

1 min

2 min

P value

Heart rate (bpm)

68 ± 13

64 ± 11

60 ± 11

< 0.001

59 ± 9

55 ± 8

54 ± 8

< 0.001

Systolic arterial pressure (mmHg)

78 ± 9

107 ± 21

123 ± 35

< 0.001

89 ± 9

121 ± 13

135 ± 20

< 0.001

Diastolic arterial pressure (mmHg)

40 ± 5

57 ± 11

61 ± 15

< 0.001

40 ± 6

58 ± 13

61 ± 13

< 0.001

Mean arterial pressure (mmHg)

53 ± 6

75 ± 15

83 ± 23

< 0.001

57 ± 6

79 ± 12

88 ± 16

< 0.001

Pulse pressure (mmHg)

38 ± 8

51 ± 14

62 ± 22

< 0.001

49 ± 11

63 ± 13

74 ± 14

< 0.001

Cardiac output (L/min)

3.7 ± 0.9

3.4 ± 0.5

3.5 ± 0.5

0.11

3.9 ± 1.0

3.7 ± 0.8

3.7 ± 0.9

0.04

Cardiac index (L/min/BSA)

2.3 ± 0.6

2.1 ± 0.3

2.2 ± 0.4

0.04

2.5 ± 0.5

2.4 ± 0.4

2.4 ± 0.5

0.028

Stroke volume (ml)

55 ± 10

54 ± 9

59 ± 9

0.01

67 ± 19

68 ± 18

70 ± 18

0.10

Stroke volume index (mL/BSA)

34 ± 5.6

34 ± 4.9

37 ± 4.9

0.01

43 ± 8.6

43 ± 8.4

44 ± 8.5

0.09

Stroke volume variation (%)

17.8 ± 7.1

17.7 ± 6.4

13.7 ± 6.7

< 0.001

7.1 ± 2.4

7.7 ± 2.5

6.8 ± 2.1

0.08

Pulse pressure variation (%)

17.7 ± 8.0

17.7 ± 8.0

13.0 ± 7.5

< 0.001

7.0 ± 3.2

7.4 ± 2.9

6.8 ± 2.3

0.52

Perfusion index (%)

5.9 ± 2.9

4.4 ± 2.2

5.1 ± 2.3

< 0.001

7.8 ± 2.4

6.4 ± 2.5

6.8 ± 2.5

0.007

Pleth variability index (%)

15.5 ± 6.6

16.3 ± 8.3

17.5 ± 7.1

0.17

10.9 ± 7.0

9.4 ± 6.1

10.2 ± 5.7

0.20

Total peripheral resistance (dyne-sec/cm5)

1209 ± 272

1798 ± 379

1953 ± 583

< 0.001

1217 ± 301

1811 ± 494

1989 ± 577

< 0.001

Dynamic arterial elastance

0.99 ± 0.20

0.99 ± 0.21

0.95 ± 0.20

0.52

0.99 ± 0.29

0.92 ± 035

1.04 ± 025

0.24