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Table 2 Intraoperative variables measurement

From: Application of remimazolam-0.6% sevoflurane anesthesia for flash visual evoked potential monitoring during pituitary adenoma resection: a non-inferiority randomized controlled trial

Variables

Group R (n = 18)

Group P (n = 18)

P

Duration of anesthesia (min)

187.1 ± 33.8

194.1 ± 39.5

0.568

Propofol dose (mg/kg/h)

—

5.3 ± 0.5

 

Remimazolam dose (mg/kg/h)

0.8 ± 0.1

—

 

MAP (mm Hg)

   

Before the induction of anesthesia

104.5 ± 6.5

102.1 ± 6.6

0.272

T0

90.5 ± 7.9

89.2 ± 6.2

0.575

T1

83.5 ± 5.8

79.50 ± 5.4

0.039*

T2

85.9 ± 8.3

83.2 ± 8.7

0.346

HR (bpm)

   

Before the induction of anesthesia

75.2 ± 13.2

76.6 ± 10.5

0.729

T0

67.1 ± 9.1

65.9 ± 5.9

0.668

T1

63.4 ± 6.8

65.2 ± 4.1

0.352

T2

62.5 ± 4.5

64.6 ± 4.4

0.164

BIS

   

Before the induction of anesthesia

94.2 ± 2.6

94.8 ± 2.0

0.830

T0

48.6 ± 4.5

51.0 ± 3.9

0.098

T1

48.4 ± 3.9

47.8 ± 5.1

0.661

T2

49.8 ± 3.6

50.9 ± 5.2

0.484

PetCO2 (mm Hg)

   

T0

32.8 ± 2.5

32.0 ± 2.3

0.303

T1

31.6 ± 2.6

31.4 ± 1.7

0.821

T2

32.3 ± 2.3

31.4 ± 1.6

0.186

Urine volume (ml)

600 (400–800)

600 (400–800)

0.542

Blood loss (ml)

50 (50–100)

50 (50-112.5)

0.164

Transfusion volume (ml)

1500 (1500–1775)

1500 (1375–2075)

0.418

  1. Variables presented as mean ± SD, median (interquartile range). *P < 0.05 vs. Group P at the same time point. MAP, mean arterial pressure; HR, heart rate; bpm, beats per minute; BIS, bispectral index; PetCO2, pressure end-tidal CO2.