Table 1 Preoperative data of the included pregnant women
Variables | Control group | Esketamine group | P value |
|---|---|---|---|
Number | 122 | 124 | Â |
Age (year), mean ± SD | 27.7 ± 4.8 | 28 ± 3.1 | 0.56 |
Pre-pregnancy BMI (kg/m2), mean ± SD | 24.1 ± 3.1 | 24.5 ± 4.7 | 0.43 |
Gestational weeks, n (%) | Â | Â | 0.85 |
 Full term  Preterm  Post term | 101 (82.77) 14 (11.48) 7 (5.74) | 106 (85.48) 12 (9.67) 6 (4.84) |  |
Pregnancy complications, n (%) | Â | Â | Â |
 Gestational diabetes  Gestational hypertension  Gestational Low thyroid | 13 (10.66) 21 (17.21) 32 (26.23) | 12 (9.68) 24 (19.35) 35 (28.23) | 0.84 0.74 0.78 |
Gravidity, n (%) | Â | Â | 0.80 |
 0  ≥1 | 47 (38.52) 75 (61.48) | 50 (40.32) 74 (59.68) |  |
Parity, n (%) | Â | Â | 0.80 |
 0  ≥1 | 61 (50) 61 (50) | 65 (52.42) 59 (47.58) | 0.80 |
Marital status, n (%) | Â | Â | 0.61 |
 Married  Divorced  Unmarried | 121 (99.18) 0 (0) 1 (0.82) | 122 (98.39) 1 (0.81) 1 (0.81) |  |
Educational level, n (%) | Â | Â | 0.43 |
 Master or above  Bachelor or below | 43 (35.25) 79 (64.75) | 50 (40.32) 74 (59.68) |  |
Stress hormone levels, mean ± SD |  |  |  |
 Free cortisol (FC) (nmol/L) | 261.51 ± 55.32 | 251.98 ± 62.23 | 0.21 |
 Atrial natriuretic peptide (ANP) (ng/mL) | 0.54 ± 0.25 | 0.59 ± 0.19 | 0.08 |
 Epinephrine (E) (ng/L) | 37.09 ± 4.32 | 35.92 ± 5.39 | 0.06 |
 Norepinephrine (NE) (ng/L) | 159.82 ± 32.21 | 155.16 ± 43.13 | 0.34 |
Inflammation-inducing factors, mean ± SD |  |  |  |
 C-reactive protein (CRP) (mg/dl) | 0.32 ± 0.11 | 0.34 ± 0.09 | 0.12 |
 Interleukin-6 (IL-6) (pg/mL) | 2.30 ± 0.7 | 2.11 ± 1.01 | 0.11 |
 Brain-derived neurotrophic factor (BDNF) (pg/mL) | 1.31 ± 0.09 | 1.29 ± 0.12 | 0.14 |
Edinburgh Postpartum Depression Scale, mean ± SD | 4.0 ± 2.1 | 3.6 ± 3.0 | 0.23 |