Table 4 Cox regression analysis of independent risk factors for 28-day mortality in patients with sepsis

LnRNA HOTTIP

2.46

1.08–5.58

0.032

4.813

1.471–15.750

0.009

Age

0.847

0.402–1.78

0.661

Gender

1.318

0.557–2.55

0.705

BMI (kg/m²)

0.967

0.242–3.867

0.962

Smoke

1.652

0.753–3.624

0.211

COPD

2.361

1.112–5.011

0.025

1.770

0.745–4.208

0.196

Cardiomyopathy

0.570

0.266–1.224

0.149

Chronic kidney failure

0.479

0.203–1.131

0.093

Cirrhosis

0.946

0.356–2.510

0.911

Abdominal infection

0.721

0.337–1.544

0.400

Respiratory infection

2.220

1.053–4.681

0.036

1.666

0.657–4.227

0.282

Skin and soft tissue infection

1.115

0.451–2.757

0.814

Bloodstream infection

0.413

0.056–3.044

0.386

CNS infection

0.334

0.077–1.450

Other infection

0.924

0.122–7.017

0.939

G⁻

0.994

0.472–2.091

0.987

G⁺

0.910

0.369–2.245

0.837

Anaerobes

0.462

0.109–1.963

0.462

Fungus

0.428

0.148–1.237

0.117

Mycoplasmas

0.694

0.162–2.970

0.623

Total culture negative

0.921

0.350–2.423

0.867

Scr

2.361

1.038–5.373

0.041

1.392

0.567–3.415

0.470

Albumin

2.014

0.497–2.225

0.072

WBC

2.073

0.936–4.589

0.072

CRP

2.371

1.083–5.189

0.031

1.682

0.636–4.452

0.295

PCT

2.285

1.006–5.189

0.048

2.046

0.633–6.611

0.232

IL-1β

2.368

1.100-5.096

0.028

1.896

0.777–4.624

0.160

IL-6

2.231

1.034–4.810

0.041

2.012

0.805–5.029

0.135

TNF-α

2.346

1.058–5.203

0.036

1.738

0.696–4.342

0.237

APAHCE II score

2.581

1.188–5.610

0.017

2.920

1.050–8.117

0.040

SOFA score

2.265

1.063–4.826

0.034

2.790

1.094–7.118

0.032