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Table 1 Basic information of the study cohort

From: Predictive value of soluble CD40L combined with APACHE II score in elderly patients with sepsis in the emergency department

Variables

Survivor(n = 55)

Non-Survivors(n = 140)

P

Age, years

71.05 ± 14.89

70.75 ± 14.81

0.001

Male, %

32 (58.2)

81 (58.0)

0.967

COPD, %

9(16.4)

31 (22.1)

0.368

Hypertension, %

26(47.2)

61(43,6)

0.640

CVD, %

9(16.4)

26(18.6)

0.718

CHF, %

20(36.4)

71(50.7)

0.071

DM, %

15(27.3)

43(30.7)

0.636

MAP, mmHg

98(86,108)

93 (83,103)

0.040

Temperature,°C

36.4 ± 0.6

36.4 ± 2.9

0.001

HR, beats/min

94(76,113)

86(75,101)

0.088

RR, bpm

20(18,22)

20(19,23)

0.035

WBC, *10^9/L

8.7(7.1,13.2)

9.3(7.0,11.6)

0.700

PLT, *10^9/L

201(152,302)

176(136,251)

0.075

Lac, mmol/L

1.2(1.0, 1.5)

1.5(1.1, 2.3)

0.002

Scr mmol/L

72.5(53.2, 84.3)

64.1(48.5, 84.9)

0.196

ALB g/L

34.8 ± 8.2

32.7 ± 8.6

0.001

AST U/L

23.8(18.2, 32.5)

28.3(19.3, 43.3)

0.064

ALT U/L

20.3(16.4,25.9)

22.2(15.6,31.9)

0.376

PCT(ng/ml)

0.05(0.05,0.07)

0.05(0.05,1.39)

0.004

CRP(mg/L)

8(5,35)

20(8,80)

0.013

sCD40L (pg/ml)

2194 (1750, 2922)

2520 (1779, 4203)

0.043

SOFA

6(5,8)

7(5,10)

0.022

APACHE II

16(13,22)

24(17,33)

0.001

  1. Abbreviation: sCD40L soluble CD40L, WBC white blood cell, PCT procalcitonin, Lac lactate, CRP C-reactive protein, ALB albumin, Scr serum creatinine, AST aspartate aminotransferase, ALT alanine transaminase, PLT platelet, MAP mean arterial pressure, RR respiratory rate, HR heart rate, SOFA Sequential Organ Failure Assessment, APACHE II Acute Physiology and Chronic Health Evaluation II, COPD chronic obstructive pulmonary disease, CVD cerebrovascular disease, CHF congestive heart failure, DM diabetes mellitus