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Table 3 The risk factors of moderate to severe acute postoperative pain in previous studies

From: A random forest algorithm-based prediction model for moderate to severe acute postoperative pain after orthopedic surgery under general anesthesia

Study (year)

Country

Number of patients

Type of surgery

Risk factors / protective factors

Vasilopoulos et al.

(2021)

USA

360

mixed surgery

younger age, female gender, higher anxiety, and more pain behaviors.

Sun et al.

(2020)

China

1164

thoracic surgery

younger age, high BMI, preoperative pain, smoking history, and number of chest tubes.

Abrecht et al.

(2019)

USA

126

orthopaedic surgery

temporal summation of pain, high BMI, number of previous knee surgeries, and female gender.

Zaslansky et al. (2018)

International

14,334

orthopaedic surgery

female gender, younger age, high BMI, chronic pain, and opioid use before surgery.

Hartwig et al. (2017)

International

192

gastric

surgery

younger age and preoperative pain.

Borges et al. (2016)

Brazil

1062

cesarean section

preoperative anxiety,

intrathecal morphine with fentanyl#.

Liu et al.

(2012)

USA

897

orthopedic surgery

female gender, younger age, high BMI, preoperative pain, preoperative use of opioids, general anesthesia, preoperative use of anti-convulsants and anti-depressants, and prior surgery at the surgical site.

  1. # represents the protective factors