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Table 5 Unintentional sedation, postoperative opioid consumption, and pain intensity among patients with or without droperidol

From: Antiemetic prophylaxis with droperidol in morphine-based intravenous patient-controlled analgesia: a propensity score matched cohort study

 

Droperidol

(n = 552)

Control

(n = 552)

p

Unintentional sedation

50 (9.1%)

43 (7.8%)

0.4481

Maximum UMSS score †

  

0.3981

0

502 (90.9%)

509 (92.2%)

 

1

22 (4.0%)

23 (4.2%)

 

2

23 (4.2%)

19 (3.4%)

 

3

5 (0.9%)

1 (0.2%)

 

4

0 (0)

0 (0)

 

Postoperative opioid consumption, MME

39.8 (23.0–68.8)

39.7 (22.2–67.4)

0.5271

Mean daily maximum NRS pain score

2.9 (2.4–3.5)

3.0 (2.4–3.5)

0.7660

Daily maximum NRS pain score

   

 POH 0–12, at rest

3.0 (2.0–4.0)

3.0 (2.0–4.0)

0.7251

 POH 0–12, during movement

5.0 (4.0–6.0)

5.0 (4.0–6.0)

0.6789

 POH 12–36, at rest

2.0 (1.0–3.0)

2.0 (2.0–3.0)

0.2208

 POH 12–36, during movement

4.0 (3.0–5.0)

4.0 (3.0–6.0)

0.4338

 POH 36–60, at rest

2.0 (1.0–2.0)

2.0 (1.0–2.0)

0.8051

 POH 36–60, during movement

3.0 (3.0–5.0)

3.0 (3.0–4.0)

0.8522

 POH 60–72, at rest

1.0 (0–2.0)

1.0 (0–2.0)

0.4523

 POH 60–72, during movement

2.0 (2.0–3.0)

2.0 (2.0–3.0)

0.5807

  1. Values were counts (percent) or median (interquartile range). MME = morphine milligram equivalent; NRS = numeric rating scale; POH, postoperative hour; UMSS = The University of Michigan Sedation Scale
  2. † 0, fully awake; 1, drowsy with closed eyes; 2, easily aroused with light tactile stimulation or simple verbal commands; 3, arousable only by strong physical stimulation; 4, unarousable