Skip to main content

Table 4 Subgroup analyses for postoperative nausea and vomiting

From: Antiemetic prophylaxis with droperidol in morphine-based intravenous patient-controlled analgesia: a propensity score matched cohort study

Subgroup

Droperidol or control

Event,

n (%)

cOR (95% CI)

p

aOR (95% CI)†

p

Apfel’s score = 1 or 2

Droperidol

8 (7.3%)

0.40 (0.17–0.96)

0.0396

0.36 (0.15–0.89)

0.0258

 

Control

19 (16.4%)

reference

 

reference

 

Apfel’s score = 3 or 4

Droperidol

59 (13.4%)

0.51 (0.36–0.73)

0.0002

0.51 (0.36–0.72)

0.0002

 

Control

101 (23.2%)

reference

 

reference

 

Age < 65 years

Droperidol

57 (12.5%)

0.47 (0.33–0.67)

< 0.0001

0.47 (0.33–0.67)

< 0.0001

 

Control

102 (23.4%)

reference

 

reference

 

Age ≥ 65 years

Droperidol

10 (10.3%)

0.63 (0.27–1.43)

0.2657

0.56 (0.24–1.30)

0.1766

 

Control

18 (15.5%)

reference

 

reference

 

Male

Droperidol

5 (5.9%)

0.40 (0.14–1.18)

0.0986

0.40 (0.14–1.18)

0.0986

 

Control

13 (13.4%)

reference

 

reference

 

Female

Droperidol

62 (13.3%)

0.50 (0.35–0.70)

< 0.0001

0.49 (0.35–0.70)

< 0.0001

 

Control

107 (23.5%)

reference

 

reference

 

Current smoker

Droperidol

4 (7.3%)

0.24 (0.07–0.81)

0.0213

0.29 (0.08–1.03)

0.0558

 

Control

12 (24.5%)

reference

 

reference

 

Not a current smoker

Droperidol

63 (12.7%)

0.53 (0.38–0.75)

0.0003

0.51 (0.37–0.72)

0.0001

 

Control

108 (21.5%)

reference

 

reference

 

Previous PONV

Droperidol

8 (32.0%)

0.71 (0.22–2.25)

0.5563

0.71 (0.22–2.3)

0.5563

 

Control

10 (40.0%)

reference

 

reference

 

No previous PONV

Droperidol

59 (11.2%)

0.48 (0.34–0.67)

< 0.0001

0.47 (0.33–0.66)

< 0.0001

 

Control

110 (20.9%)

reference

 

reference

 

Neuraxial anesthesia

Droperidol

26 (14.1%)

0.54 (0.32–0.94)

0.0282

0.54 (0.32–0.94)

0.0286

 

Control

40 (23.3%)

reference

 

reference

 

General anesthesia

Droperidol

41 (11.2%)

0.48 (0.32–0.72)

0.0004

0.45 (0.30–0.69)

0.0002

 

Control

79 (20.9%)

reference

 

reference

 

Use of volatile anesthetics

Droperidol

41 (11.1%)

0.47 (0.31–0.71)

0.0003

0.45 (0.30–0.68)

0.0002

 

Control

80 (21.1%)

reference

 

reference

 

No use of volatile anesthetics

Droperidol

26 (14.1%)

0.54 (0.32–0.94)

0.0282

0.54 (0.32–0.94)

0.0286

 

Control

40 (23.3%)

reference

 

reference

 

Use of neostigmine

Droperidol

13 (10.6%)

0.47 (0.23–0.96)

0.0371

0.49 (0.24–1.02)

0.0569

 

Control

27 (20.2%)

reference

 

reference

 

Use of sugammadex

Droperidol

27 (11.2%)

0.46 (0.28–0.76)

0.0023

0.42 (0.25–0.70)

0.0009

 

Control

52 (21.7%)

reference

 

reference

 

Intraoperative use of dexamethasone

Droperidol

39 (11.3%)

0.49 (0.32–0.74)

0.0008

0.46 (0.30–0.71)

0.0004

 

Control

74 (20.7%)

reference

 

reference

 

No intraoperative use of dexamethasone

Droperidol

28 (13.5%)

0.51 (0.30–0.85)

0.0100

0.51 (0.30–0.85)

0.0101

 

Control

46 (23.6%)

reference

 

reference

 
  1. aOR, adjusted odds ratio; CI, confidence interval; cOR, crude odds ratio; PONV, postoperative nausea and vomiting
  2. † Adjusted for sex and previous history of PONV.
Back to article page

BMC Anesthesiology

ISSN: 1471-2253

Contact us