Antiemetic prophylaxis with droperidol in morphine-based intravenous patient-controlled analgesia: a propensity score matched cohort study

Table 3 Rates and severity of postoperative nausea and vomiting among patients with or without receiving droperidol

	Droperidol	Control	cOR (95% CI)	p	aOR (95% CI)^†	p
	Event, n (%)	Event, n (%)	cOR (95% CI)	p	aOR (95% CI)^†	p
All PONV	67 (12.1%)	120 (21.7%)	0.50 (0.36–0.69)	0.0046	0.49 (0.35–0.67)	< 0.0001
POH 0–12	17 (3.1%)	42 (7.6%)	0.39 (0.22–0.69)	0.0012	0.37 (0.21–0.67)	0.0009
Mild	13 (2.4%)	28 (5.1%)
Moderate	3 (0.5%)	9 (1.6%)
Severe	1 (0.2%)	5 (0.9%)
POH 12–36	45 (8.2%)	69 (12.5%)	0.62 (0.42–0.92)	0.0184	0.61 (0.41–0.91)	0.0151
Mild	32 (5.8%)	50 (9.1%)
Moderate	9 (1.6%)	17 (3.1%)
Severe	4 (0.7%)	2 (0.4%)
POH 36–60	12 (2.2%)	23 (4.2%)	0.51 (0.25–1.04)	0.0632	0.52 (0.25–1.05)	0.0673
Mild	7 (1.3%)	21 (3.8%)
Moderate	3 (0.5%)	2 (0.4%)
Severe	2 (0.4%)	0 (0)
POH 60–72	6 (1.1%)	6 (1.1%)	1.00 (0.32–3.13)	0.9949	0.99 (0.32–3.09)	0.9799
Mild	6 (1.1%)	5 (0.9%)
Moderate	0 (0)	1 (0.2%)
Severe	0 (0)	0 (0)
Need for antiemetics	71 (12.9%)	110 (19.9%)	0.59 (0.43–0.82)	0.0016	0.58 (0.41–0.80)	0.0011

aOR, adjusted odds ratio; CI, confidence interval; cOR, crude odds ratio; POH, postoperative hour
† Adjusted for sex and previous history of PONV.

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