Table 1 Baseline clinical characteristics and intraoperative variables of Group L and Group H
Clinical variable | Group L, n = 44 | Group H, n = 44 | P value |
|---|---|---|---|
Preoperative index | |||
Age (y) | 66.0(62.3–71.8) | 68.0(65.3–70.0) | 0.313 |
BMI (kg/m2) | 24.1(21.3–25.1) | 24.2(23.0–28.0) | 0.502 |
Gender (female) | 18(40.9) | 23(52.3) | 0.285 |
MMSE0 | 28.0(26.0–29.0) | 27.5(26.0–28.0) | 0.259 |
ASA | 0.560 | ||
III n (%) | 6(13.6) | 8(18.2) | |
IV n (%) | 38(86.4) | 36(81.8) | |
Type of surgery | > 0.999 | ||
Valve surgery n (%) | 39(88.6) | 39(88.6) | |
Aortic root surgery n (%) | 5(11.4) | 5(11.4) | |
EF (%) | 64.2 ± 7.9 | 63.8 ± 6.9 | 0.797 |
Educational level < 5 years n(%) | 20(45.5) | 23(52.3) | 0.522 |
CAS ≥ 50% n (%) | 2(4.5) | 10(22.7) | 0.013 |
Smoking n (%) | 0(0) | 1(2.3) | > 0.999# |
Hypertension n (%) | 25(56.8) | 13(29.5) | 0.010 |
Diabetes n (%) | 6(13.6) | 6(13.6) | > 0.999 |
Haemoglobin(g/L) | 126.4 ± 16.3 | 120.1 ± 16.7 | 0.076 |
Inoperative index | |||
CPB time (min) | 119.5(100.3–155.0) | 114.5(101.0-159.0) | 0.897 |
Benzenediazepines use n (%) | 38(86.4) | 38(86.4) | > 0.999 |
Penehyclidine hydrochloride use n (%) | 35(79.5) | 39(88.6) | 0.244 |
Length of surgery (min) | 280.0(250.0-351.3) | 290.0(255.0-347.5) | 0.652 |
Anaesthesia time (min) | 330.0(296.3-393.8) | 345.0(320.0-400.0) | 0.316 |
Sufentanil (ug) | 350.0(311.8–395.0) | 350.0(317.3-406.8) | 0.698 |
Propofol (mg) | 1100.0(989.5-1283.5) | 1120.0(1000.0-1200.0) | 0.776 |
DEX infusion time (h) | 18.5(14.0–22.0) | 20.0(14.0-26.8) | 0.410 |