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Table 2 Comparisons of intraoperative characteristics between two groups

From: The effect of goal-directed hemodynamic therapy on clinical outcomes in patients undergoing radical cystectomy: a randomized controlled trial

Variables

GDHT (N = 39)

Control (N = 36)

Risk, median, or mean difference (95% CI)

P-value

Type of diversion, n (%)

   

0.999

 Ileal conduit

8 (20.5)

7 (19.4)

0.01 (-0.17 to 0.19)

 

 Neobladder

31 (79.5)

29 (80.6)

-0.01 (-0.19 to 0.17)

 

Duration of surgery (min)

225.0 (195.0–250.0)

227.5 (202.5–260.0)

-2.5 (-30.0 to 12.5)

0.339

Duration of anesthesia (min)

260.0 (237.5–302.5)

270.0 (250.0–307.5)

-10.0 (-35.0 to 10.0)

0.201

Anesthetic agents

   

0.218

 Sevoflurane

9 (23.1)

14 (38.9)

-0.16 (-0.37 to 0.05)

 

 Desflurane

30 (76.9)

22 (61.1)

0.16 (-0.05 to 0.37)

 

Total crystalloid administered (ml)

2700.0 (2175.0–3250.0)

2900.0 (1950.0–3700.0)

-200.0 (-875.0 to 825.0)

0.714

Estimated blood loss (ml)

700.0 (500.0–1000.0)

700.0 (450.0–1250.0)

0 (-350 to 350)

0.671

RBC transfusion (pack)

0.2 ± 0.5

0.3 ± 0.8

-0.15 (-0.47 to 0.16)

0.330

Medications

    

 Use of norepinephrine, n (%)

5 (12.8)

1 (2.8)

0.10 (-0.02 to 0.22)

0.240

 Number of rescue drugs administered, n

5.0 (3.0–8.5)

6.0 (3.5–9.0)

-1.0 (-5.0 to 1.0)

0.166

 Amount of ephedrine (mg)

10.0 (5.0–20.0)

17.5 (5.0–30.0)

-7.5 (-15.0 to 2.5)

0.171

 Amount of phenylephrine (µg)

0.0 (0.0–65.0)

30.0 (0.0–140.0)

-30.0 (-75.0 to 20.0)

0.131

 Amount of remifentanil (µg)

1200.0 (1000.0–1481.5)

1450.0 (1050.0–2000.0)

-250.0 (-635.5 to 100.0)

0.027

Area under MAP (mmHg * min)

    

 < 65 mmHg

48.0 (14.5–85.5)

56.5 (19.0–94.5)

-8.5 (-36.0 to 31.0)

0.758

 < 60 mmHg

5.0 (0.0–46.5)

9.2 (0.0–33.5)

-4.3 (-17.5 to 12.0)

0.913

 < 55 mmHg

0.0 (0.0–1.5)

0.0 (0.0–11.0)

0.0 (0.0 to 0.0)

0.664

Extubation in ICU, n (%)

1 (2.6)

0 (0.0)

0.03 (-0.02 to 0.08)

0.999

  1. Data are expressed as number (percentage), median (interquartile range), or mean ± standard deviation
  2. GDHT: goal-directed hemodynamic therapy, CI: confidence interval, RBC: red blood cell, MAP: mean arterial pressure, ICU: intensive care unit