Table 1 Comparisons of demographics between survivors and non–survivors
Baseline characteristics | Survivors (n = 936) | Non-survivors (n = 365) | p value |
|---|---|---|---|
Age, years | 61.3 (48.5–74.0) | 68.3 (56.0–79.0) | < 0.001 |
Male gender | 508 / 936 (54.3) | 191 / 365 (52.3) | 0.527 |
Weight, kg | 82.7 (69.0–99.0) | 78.0 (65.0–92.0) | < 0.001 |
Height, cm | 170 (163–178) | 168 (160–176) | 0.015 |
BMI, kg/m2 | 28.4 (24.3–33.9) | 26.8 (23.2–32.1) | 0.001 |
PBW, kg | 63.9 (54.7–73.1) | 61.7 (52.5–71.8) | 0.026 |
Admission type | 0.001 | ||
Selective | 82 / 936 (8.8) | 11 / 365 (3.0) | |
Emergency | 836 / 936 (89.3) | 349 / 365 (95.6) | |
Urgent | 18 / 936 (1.9) | 5 / 365 (1.4) | |
Ethnicity | 0.005 | ||
White | 647 / 936 (69.1) | 223 / 365 (61.1) | |
Black | 85 / 936 (9.1) | 31 / 365 (8.5) | |
Other | 204 / 936 (21.8) | 111 / 365 (30.4) | |
Comorbidities | |||
CHF | 170 / 936 (18.1) | 78 / 365 (21.4) | 0.186 |
Cardiac arrhythmias | 212 / 936 (22.6) | 110 / 365 (30.1) | 0.005 |
Valvular disease | 53 / 936 (5.7) | 30 / 365 (8.2) | 0.090 |
Hypertension | 143 / 936 (15.3) | 56 / 365 (15.3) | 0.977 |
Diabetes | 260 / 936 (27.8) | 119 / 365 (32.6) | 0.085 |
Neurological condition | 139 / 936 (14.9) | 46 / 365 (12.6) | 0.297 |
Chronic pulmonary condition | 215 / 936 (23.0) | 88 / 365 (24.1) | 0.662 |
Renal failure | 160 / 936 (17.1) | 75 / 365 (20.5) | 0.146 |
Liver condition | 95 / 936 (10.1) | 50 / 365 (13.7) | 0.068 |
Severity of illness | |||
APACHE III | 51 (38–69) | 65 (50–85) | < 0.001 |
Vital signs in the beginning of ventilation | |||
Heart rate, bpm | 89 (77–103) | 89 (75–103) | 0.496 |
MAP, mmHg | 82 (76–91) | 83 (76–91) | 0.465 |
SpO2, % | 98 (96–99) | 98 (96–99) | 0.016 |
Temperature, °C | 37.0 (36.4–37.5) | 36.7 (36.1–37.3) | < 0.001 |
Laboratory in the beginning of ventilation | |||
pH | 7.36 (7.28–7.42) | 7.34 (7.26–7.41) | 0.002 |
PaO2 / FiO2, mmHg | 238 (152–351) | 213 (132–334) | 0.047 |
PaCO2, mmHg | 41 (37–49) | 40 (34–49) | 0.059 |
Second day of ventilation parameters | |||
Tidal volume, ml/kg PBW | 7.8 (6.8–8.8) | 7.9 (6.8–8.8) | 0.880 |
PEEP, cmH2O | 7 (5–10) | 7 (5–10) | 0.016 |
PIP, cmH2O | 24 (20–28) | 26 (22–30) | < 0.001 |
Respiratory rate, bpm | 20 (17–23) | 21 (18–24) | < 0.001 |
Minute ventilation, L/min | 9.2 (7.7–11.1) | 9.6 (8.6–11.7) | 0.009 |
MP, J/min | 13.5 (10.2–18.4) | 14.7 (11.3–19.9) | < 0.001 |
norMP, 10− 3 J/min/kg | 222.1 (161.3–288.0) | 245.4 (183.8–333.4) | < 0.001 |