Table 1 Demographics and study characteristics
Study (author, year, location) | Study type | Sample size (n) | Age, years Mean ± SD | Gender (% female) | Setting | Outcome |
|---|---|---|---|---|---|---|
Bosnes, 2020 (Norway) [26] | PC | 106 | 73.4 ± 8.4 | 53 | NR | Dementia |
Hess, 2020 (US) [27] | PC | 124 | 73.59 ± 6.26 | 82 | Community Outpatient clinic | Dementia |
Guerdoux-Ninot, 2019 (France) [28] | PC | 488 | Healthy controls: 56.5 ± 15.1 Functional patients: 57.1 ± 11.5 naMCI patients: 69 ± 8.5 aMCI patients: 70.6 ± 10.5 AD patients: 72.8 ± 7.4 | Healthy controls: 106 Functional patients: 66 na-MCI patients: 42 a-MCI patients: 48 AD patients: 32 | Community Outpatient clinic | aMCI naMCI AD |
Kim, 2019 (South Korea) [29] | PC | 420 | 75 ± 6 | 46 | Outpatient clinic | Dementia MCI |
Howland, 2017 (US) [30] | PC | 281 | 78 | 72 | Outpatient clinic Community | MCI |
Markova, 2017 (Czech Republic) [31] | RC | 340 | 75 ± 8 | 55 | Community | MCI |
Papaliagkas, 2017 (Greece) [32] | PC | 81 | Older adults: 70 ± 4 Older-old adults: 84 ± 3 | Older adults: 42 Older-old adults: 64 | NR | MCI |
Yim, 2017 (South Korea) [33] | PC | 814 | Cognition intact: 69 ± 7. MCI: 73 ± 7. Dementia: 73 ± 9 Overall cognitive disorder: 73 ± 9 | 64 | Outpatient clinic | Dementia MCI |
Avila-Villanueva, 2016 (Spain) [34] | PC | 844 | Control: 74 ± 4 MCI: 76 ± 4 | Control: 63 MCI: 50 | Community | MCI |
Tew, 2015 (Singapore) [35] | PC | 245 | Dementia: 77 ± 8 No dementia: 68 ± 7 | Dementia: 64 No dementia: 72 | Outpatient clinic Community | Dementia |
Valech, 2015 (Spain) [36] | PC | 217 | Control: 65 ± 8 Pre-AD: 69 ± 8 NonA-CI: 63 ± 10 A-CI: 70 ± 8 | Control: 68 Pre-AD: 79 NonAB-CI: 42 AB-CI: 62 | Outpatient clinic Community | aMCI |
Li, 2013 (China) [37] | PC | 356 | 72 ± 9 | 58 | Community | MCI |
Ramlall, 2013 (South Africa) [38] | PC | 140 | 75 ± 9 | 69 | Community | Dementia MCI |
Snitz, 2012 (US) [39] | PC; secondary analysis | 3495 | 78 ± 7 | 62 | Community | aMCI |
Abbate, 2011 (Italy) [40] | RC | 119 | 77 ± 6 | 62 | Outpatient clinic | MCI |
Amariglio, 2011 (US) [41] | PC | 16,964 | 74 | 100 | Community | MCI |
Ayalon, 2011 (US) [42] | PC | 647 | Cognition intact: 77 ± 0 CIND: 81 ± 1 Dementia: 84 ± 1 | 66 | NR | Dementia MCI |
Gavett, 2011 (US) [43] | PC | 384 | Initial visit: 70 ± 7 Final visit: 73 ± 7 | 100 | Community | MCI |
Calabria, 2010 (Spain) [44] | PC | 112 | 71 ± 6 | 78 | Community | aMCI |
Youn, 2009 (S. Korea) [45] | PC | 1651 | 74 ± 8 | 57 | NR | Dementia |
Snitz, 2008 (US) [47] | PC | 276 | 73 ± 6 | 58 | Outpatient clinic | aMCI |
Lam, 2005 (Hong Kong) [46] | PC | 306 | 79 ± 7 | NR | Community | AD MCI |