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Table 2 Results for linear mixed-effects and linear models of pain variables versus interaction of technique and time period, adjusting for repeated measurements over time

From: A comparison of ultrasound guided bilateral single injection shot Erector Spinae Plane blocks versus wound infiltration for post-operative analgesia in laparoscopic assisted colonic surgery- a prospective randomised study

Outcome

Interaction/Predictor

Period - hours

ESPBN = 33 mean (SD)

WIN = 34 mean (SD)

Mean differencea(95% CI)

Comparison P value

Interaction/Global P value

Intraoperative fentanyl use

Technique

 

469.7 (198.4)

491.3 (265.4)

−21.6 (− 136.2, 93.0)

 

0.708

Rest pain

Period*Technique

0

1.6 (2.5)

1.9 (3.1)

−0.3 (−1.5, 0.9)

0.606

0.892

1

3.3 (2.2)

3.8 (2.4)

−0.5 (− 1.7, 0.7)

0.382

 

24

2.4 (2.0)

3.0 (2.2)

−0.6 (−1.8, 0.5)

0.285

 

Cough pain

Period*Technique

0

2.3 (3.3)

2.9 (3.5)

−0.6 (−2.0, 0.8)

0.375

0.953

1

4.4 (2.4)

4.8 (2.8)

−0.4 (−1.7, 1.0)

0.595

 

24

5.3 (2.3)

5.9 (2.5)

−0.5 (−1.9, 0.8)

0.431

 

Cumulative Fentanyl use

Period*Technique

1

117.6 (107.8)

104.1 (111.4)

13.5 (−200.0, 226.8)

0.900

0.911

24

760.3 (682.1)

730.7 (527.3)

29.6 (− 183.8, 242.9)

0.783

 

Total fentanyl usedb

Technique

 

877.9 (731.9)

834.9 (557.0)

43.0 (− 273.7, 359.8)

 

0.787

  1. ESPB denotes Erector Spinae Plane block, WI denotes wound infiltration, PACU Post anaesthetic care unit, CI Confidence interval
  2. aThe comparison is ESPB vs WI
  3. bTotal fentanyl used is the amount used during PACU and day one