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Table 3 Breathing pattern and gas exchange parameters during the different experimental conditions

From: Peep titration based on the open lung approach during one lung ventilation in thoracic surgery: a physiological study

 

OLVpre-OLA

OLVpost-OLA

p-value

VT (ml/Kg PBW)

5.9±0.9

5.9±0.7

0.47

RR (breaths/min)

18±1

18±1

0.77

PAO, PLAT (cmH2O)

12.8±1.6

16.7±2.2*

0.003

PEEPext (cmH2O)

0

6±0.8

0.3

PEEPTOT, RS (cmH2O)

3.6±1.4

9.8±1.2*

0.0001

ΔPRS (cmH2O)

9.24±0.4

6.88±0.6*

0.001

ΔPL (cmH2O)

8.1±0.5

5.7±0.5*

0.015

CRS (ml/cmH2O)

45±11.3

62±13.4*

0.001

CL (ml/cmH2O)

56.17±18.18

71.06 ±12.25*

0.0013

CCW (ml/cmH2O)

310±15.4

312±14.2

NS

Raw (cmH2O/L/s)

11.24±3.72

7.42±4.21*

0.004

pH

7.37±0.05

7.37±0.03

NS

PaCO2 (mmHg)

44±2.9

43±3.8

NS

PaO2/FiO2(mmHg)

205±73

313±86*

0.004

  1. Pared T-test was used for the comparison of continuous variables. Data are expressed as mean ± SD
  2. CRS respiratory system compliance, CL lung compliance, CCW chest wall compliance, ΔPRS respiratory system driving pressure, ΔPL transpulmonary driving pressure, FiO2 inspiratory oxygen fraction, PaO2 arterial oxygen tension, PaCO2 arterial carbon dioxide tension, PEEP positive end expiratory pressure, PEEPext external PEEP, PEEPTOT,RS respiratory system total PEEP, PAO,PLAT respiratory system plateau airways pressure, RR respiratory rate, VT tidal volume
  3. statistical significant when compared to OLVpre-OLA