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Table 4 Case-matched study: demographic and clinical characteristics of patients mechanically ventilated for at least 14 days

From: Is tracheostomy a better choice than translaryngeal intubation for critically ill patients requiring mechanical ventilation for more than 14 days? A comparison of short-term outcomes

  Translaryngeal tube (n = 164) Tracheostomy (n = 164) p value
Age, years 68 (54–77) 64 (51–74) 0.749
Male, n (%) 108 (66) 110 (67) 0.899
MICU, n (%) 87 (53) 94 (57) 0.464
APACHE II score 24.3 ± 7.4 23.2 ± 7.5 0.448
Do-not-resuscitate order 44 (27) 39 (24) 0.568
NIV after extubation, n (%) 26 (16) 24 (15) 0.871
Diagnosis of ICU admission, n (%)
Pneumonia 75 (46) 94 (57) 0.033
Sepsis 68 (42) 68 (42) 1.000
Cardiovascular or vascular disorder 13 (8) 12 (7) 1.000
Trauma 17 (10) 23 (14) 0.361
Brain disorder 70 (43) 76 (46) 0.571
Gastrointestinal disorder 42 (26) 51 (31) 0.328
CCI score 2 (1–3) 2 (0–3) 0.836
Comorbidities, n (%)
Diabetes 55 (34) 66 (40) 0.235
Chronic lung disease 36 (22) 37 (23) 1.000
Chronic heart disease 30 (18) 29 (18) 1.000
Chronic liver disease 14 (9) 12 (7) 0.839
Chronic renal disease 35 (21) 30 (18) 0.575
Malignancy 44 (27) 44 (27) 1.000
Connective tissue disease 1 (1) 1 (1) 1.000
Neuromuscular disease 8 (5) 10 (6) 0.804
PaO2/FiO2
w1 302.1 ± 137.7 266.6 ± 132.0 0.899
w2 312.0 ± 101.9 293.6 ± 110.0 0.734
WBC (× 103/μl)
w1 11.9 (9.0–14.4) 10.8 (8.4–15.9) 0.901
w2 10.7 (8.1–12.8) 11.5 (7.9–14.9) 0.449
Platelet (× 103/μl)
w1 181.0 (122.0–226.0) 148.0 (102.5–195.3) 0.516
w2 183.3 ± 100.6 170.1 ± 99.2 0.978
BUN (mg/dl)
w1 18.0 (13.0–35.0) 28.5 (14.3–49.8) 0.774
w2 38.0 (24.0–69.0) 44.0 (22.0–65.3) 0.706
Creatinine (mg/dl)
w1 1.1 (0.8–2.5) 1.0 (0.8–2.0) 0.111
w2 1.3 (0.7–2.4) 1.0 (0.6–2.4) 0.327
Transition to regional hospitals, n (%)a 39 (24) 40 (24) 0.808
Time to transition, daysb 27 (21–45) 54 (44–80) 0.009
Duration of MV, daysb 28 (21–35) 37 (25–51) <0.001
Weaning rate, n (%)a 65 (40) 113 (69) <0.001
ICU length of stay, daysb 27 (21–34) 40 (25–55) <0.001
Hospital length of stay, daysb 30 (23–46) 59 (45–94) <0.001
ICU mortality, n (%)a 63 (38) 28 (17) <0.001
Hospital mortality, n (%)a 76 (46) 36 (22) <0.001
  1. Data are presented as median (interquartile range) or mean ± standard deviation unless otherwise stated
  2. aCompared with general estimation equation analysis, adjusted for pneumonia
  3. bCompared with mixed-model analysis, adjusted for pneumonia
  4. Abbreviations: APACHE II Acute physiology and chronic health evaluation II, BUN Blood urea nitrogen, CCI Charlson comorbidity index, MICU Medical intensive care unit, MV Mechanical ventilation, NIV Noninvasive ventilation, ICU Intensive care unit, PaO 2 /FiO 2 Ratio of the partial pressure of arterial oxygen to the fraction of inspired oxygen, WBC White blood cell count, w1 Data collected within days 1–5 after ICU admission, w2 Data collected within days 8–12 after ICU admission